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M365 refuses since we ran a new script with 4.7.500 or throttle

Microsoft 365 throttles per user and per tenant. Per user: 30 messages per minute, 10,000 recipients per day. Per tenant via Exchange Online relay: 10,000 recipients/day default. A 4.4.62, 4.4.7 or 4.7.500 cap means throttle, not permanent block.

Try this first

  1. 1Read the NDR. 4.7.500-901 = sender exceeded message rate. 4.7.28 = throttling. 5.0.350 = relay denied.
  2. 2Spread sending over time. 30/minute means a loop with sleep of 2 seconds between messages works past the cap.
  3. 3Batch jobs above 10k/day: don't use an M365 mailbox. Use an ESP or Azure Communication Services Email.
  4. 4SMTP relay from on-prem apps: use a Receive Connector with IP allowlist and dedicated quota, not user AUTH.
  5. 5Monitor in Exchange admin → Mailflow → Message Trace. You see per-user volume there.

When to bring us in

Sending more than 5k recipients/day from one mailbox routinely means you're on the wrong tool. Migrate to an ESP, it's cheaper and you keep reputation.

See also

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