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Bounce with 5.4.1: 'recipient address rejected, access denied'

5.4.1 points to a routing or access issue at the recipient. The address may exist, but a rule or connector blocks it.

Try this first

  1. 1Ask the recipient to check whether your address is blocked
  2. 2Check transport rules in their Exchange Online tenant
  3. 3Send a test from a different domain to rule out a sender issue
  4. 4On hybrid setups: check connector routing between on-prem and cloud

When to bring us in

5.4.1 can't be fixed on the sending side if the recipient denies access, they have to look.

See also

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